Protein Synthesis
Protein Synthesis: The Process of Building Proteins
Protein synthesis is the process by which cells create proteins from amino acids. It's a complex process that involves two main steps: transcription and translation.
Transcription
* Initiation: The process begins when an enzyme called RNA polymerase binds to a specific sequence of DNA called a promoter.
* Elongation: The RNA polymerase moves along the DNA strand, reading the genetic code and synthesizing a complementary RNA molecule called a messenger RNA (mRNA).
* Termination: The RNA polymerase reaches a termination signal on the DNA, and the mRNA molecule is released.
Translation
* Initiation: The mRNA molecule binds to a ribosome, and an initiator tRNA molecule carrying the amino acid methionine binds to the start codon on the mRNA.
* Elongation: The ribosome moves along the mRNA, reading the genetic code in codons (groups of three nucleotides). Each codon corresponds to a specific amino acid. Transfer RNA (tRNA) molecules carrying the corresponding amino acids bind to the mRNA codons. The amino acids are linked together by peptide bonds to form a protein chain.
* Termination: The ribosome reaches a stop codon on the mRNA, and the protein chain is released.
Key components involved in protein synthesis:
* DNA: The genetic blueprint that contains the instructions for protein synthesis.
* RNA: Messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA) are involved in the transcription and translation processes.
* Ribosomes: Cellular organelles that read the mRNA and assemble the protein chain.
* Amino acids: The building blocks of proteins.
* tRNA: Molecules that carry amino acids to the ribosome.
* Enzymes: Various enzymes, such as RNA polymerase and aminoacyl-tRNA synthetases, are involved in the process.